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KMID : 1001020060040020091
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Journal of Urologic Oncology
2006 Volume.4 No. 2 p.91 ~ p.94
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Epithelioid Angiomyolipoma of the Kidney Misdiagnosed as a Renal Cell Carcinoma
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Ha U-Syn
Lee Jun-Ha
Lee Kwang-Bae
Choi Hang-Won
Cho Dae-Haeng
Lee Chung-Bum
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Abstract
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Epithelioid angiomyolipoma is a recently recognized variant of angiomyolipoma, which is characterized by the presence of polygonal cells with densely eosinophilic cytoplasm and varying degrees of nuclear atypia. We report a case of renal epithelioid angiomyolipoma misdiagnosed as a renal cell carcinoma that occurred in a 46-year-old woman. Pathologically, the tumor was composed of diffuse sheets of epithelioid cells, which had pleomorphic and hyperchromatic nuclei with densely eosinophilic cytoplasm and were positive in HMB-45 and smooth muscle actin. There was no expression of cytokeratin, epithelial membrane antigen, vimentin, myoglobin, S-100 protein, estrogen receptor and progesterone receptor. After radical nephrectomy, the patient showed no evidence of recurrence or metastasis until now.
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KEYWORD
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Epithelioid cell, Angiomyolipoma, Kidney
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